Special Focus Issue: Transdermal, Topical and Folicular Drug Delivery Systems
نویسندگان
چکیده
منابع مشابه
Novel transdermal drug delivery systems
Background and aim: Eczema is a common inflammatory skin disease. Although history and physical examination are important in diagnosis of allergen, because of extent of environmental allergens, those are not simply recognized. The objective of this study was to determine allergens in patients with contact or atopic dermatitis referred to Razi hospital.Materials and Meth...
متن کاملInnovative Strategies for Enhancing Topical and Transdermal Drug Delivery
Abstact: Historically, the skin was thought to be a simple homogenous barrier. However, it is now known to be a highly specialised organ, and plays a key role in homeostasis. The protective properties of the skin are provided by the outermost layer, the epidermis, which safeguards against chemical, microbial, and physical attack. The exceptional barrier properties of the skin result in it being...
متن کاملDrug crystallization - implications for topical and transdermal delivery.
INTRODUCTION Crystallization of actives in skin following topical application was suggested by studies in the 1950s and 1960s but is poorly understood. In contrast, the problem of crystallization of actives on skin and in transdermal formulations has been known for many years. AREAS COVERED With respect to crystallization in skin, this review describes early reports of a skin 'reservoir' and ...
متن کاملPolymers in Transdermal Drug Delivery Systems
a multidisciplinary activity that encompasses ● fundamental feasibility studies starting from the selection of a drug molecule to the demonstration of sufficient drug flux in an ex vivo and/or in vivo model ● the fabrication of a drug delivery system that meets all the stringent needs that are specific to the drug molecule (physicochemical and stability factors), the patient (comfort and cosmet...
متن کاملTransdermal drug delivery systems: skin perturbation devices.
Human skin serves a protective function by imposing physicochemical limitations to the type of permeant that can traverse the barrier. For a drug to be delivered passively via the skin it needs to have a suitable lipophilicity and a molecular weight < 500 Da. The number of commercially available products based on transdermal or dermal delivery has been limited by these requirements. In recent y...
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ژورنال
عنوان ژورنال: Drug Development and Industrial Pharmacy
سال: 2016
ISSN: 0363-9045,1520-5762
DOI: 10.3109/03639045.2016.1169634